Rasiklal M. Dhariwal Institute of Pharmaceutical Education and Research, Acharya Anand Rushiji Marg, Chinchwad, Pune- 411019, Maharashtra, India
World Journal of Advanced Research and Reviews, 2020, 06(01),019-024
Article DOI: 10.30574/wjarr.2020.6.1.0078
DOI url: https://doi.org/10.30574/wjarr.2020.6.1.0078
Received on 24 March 2020; revised on 29 March 2020; accepted on 30 March 2020
Aliskiren (AL) is classified as angiotensin converting enzyme inhibitors (ACEIs) used as antihypertensive drug it acts by dilating blood vessel. These dilation of blood vessel caused due to the renin inhibition. There have been numerous methods developed so far for quantitative estimation of AL in bulk and pharmaceutical dosage form. Pharmaceutical analytical methods include UV Visible Spectrophotometry, Reversed Phase High Performance Liquid Chromatography and hyphenated techniques like Liquid chromatography- Mass Spectrometry. This review paper includes various publications focuses on advanced analytical methods. The chromatographic methods primarily RP-HPLC and LC-MS found more promising and sensitive compared to other pharmaceutical methods.
Aliskiren; High performance liquid Chromatography (HPLC) and Hyphenated techniques
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Patil Sheetal Vikas, Nalawade Anup Kishor, Nalawade Rohit Deepak and Ghode Shweta Prashant. Aliskiren: analytical review for estimation in pharmaceutical formulations. World Journal of Advanced Research and Reviews, 2020, 06(01),019-024. Article DOI: https://doi.org/10.30574/wjarr.2020.6.1.0078
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