Breast squamous cell carcinoma: Case report and review of the literature

Squamous cell carcinoma (SCC) of the breast is a rare and aggressive form of breast cancer, classified as a metaplastic carcinoma. Diagnosis of this carcinoma is challenging due to the absence of distinctive clinical or radiological features. Histopathological conformation is essential, and immunochemistry typically shows negativity for hormone receptors and HER2, with positive markers such as CK5/6 and P40. Treatment strategies are not well defined, but platinum-based chemotherapy has shown promising results in some cases. Radiotherapy can serve both curative and palliative purposes depending on disease stage. We report the case of a 57-year-old patient treated in our department with chemotherapy and radiotherapy.