Exploring the therapeutic potential of flaxseed oil: Insights from pre-clinical and clinical research

Flaxseed is also known as linseed which is derived from linseed plant. This has in folk medicine been used as Fiber and oil for health benefits in health and nutrition in treating a number of diseases. Flaxseed oil contains unsaturated fatty acids such as omega-3 fatty acids, α linolenic acid (ALA), oleic acid and palmitic and stearic acid. The various uses of flaxseed oil include cardiovascular health, diabetes, weight management, cancer, digestive problems, anti-inflammatory properties, high blood pressure, hormonal imbalance, obesity, neurological disorders and others. Flaxseed oil also aids in strengthening the immune system. It has also become more popular due to its benefits to the health of individuals. Flaxseed biochemical composition includes protein (20-30%), Dietary Fibers, Lignans, and Minerals. It is used in bakery products as food ingredient flaxseed oil. Flaxseed oil can also be applied in the formulation of skin care products for moisturizing, anti-aging and skin conditions. It acts as an anti-inflammatory and has positive effects on wound healing that impacts the size of wounds on burn patients. It can also be used as a Dietary Supplement as it is a powerful supplement which can be beneficial in so many health disorders. The concentration and potential effect of flaxseed oil depend on research done on animals and humans recently and the uses in commerce. This review will summarize the preclinical and clinical studies investigating flaxseed oil and its potential uses and therapeutic effects for various diseases. Thus, the primary source of data analyzed in the present paper was the literature review based on articles that concerned the topic of flaxseed oil and its impact on the human body. Information was obtained from preclinical studies, RCTs, and meta-analyses in the peer-reviewed literature.