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Ondansetron: A selective 5HT3 receptor antagonist and it advances in drug delivery system

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  • Ondansetron: A selective 5HT3 receptor antagonist and it advances in drug delivery system

Supriya Subhas Jana, Mrunmayi Deepak Lad, Suranya Subramanian and Dhanashree Prakash Sanap *

Bharati Vidyapeeth’s College of Pharmacy, Sector-8, C.B.D. Belapur, Navi Mumbai, Maharashtra – 400614, India.

Review Article
 

World Journal of Advanced Research and Reviews, 2022, 16(03), 068-077
Article DOI: 10.30574/wjarr.2022.16.3.1275
DOI url: https://doi.org/10.30574/wjarr.2022.16.3.1275

Received on 15 October 2022; revised on 29 November 2022; accepted on 01 December 2022

Ondansetron is a serotonin (5HT3) receptor antagonist used for the prevention and treatment of postoperative nausea and vomiting. It is available in many dosage forms in the market. Various analytical methods used for the determination of Ondansetron have been studied in this review article such as UV spectroscopy, mass spectroscopy, high-performance liquid chromatography, high-performance thin layer chromatography, a new electrospray ionization mass spectrometry etc. Ondansetron in human plasma can be estimated using this method. With time many advances have been made in the formulation aspects of Ondansetron, such as now a days it is available in floating drug delivery, transdermal as well as gastroretentive and orodispersible drug delivery system. New novel technologies are also mentioned in this review article related to 3D printing, nanofibers etc

Ondansetron hydrochloride; Gastro retentive floating tablet; Validation; Spectrophotometric; 3D printing

https://wjarr.com/node/4706

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Supriya Subhas Jana, Mrunmayi Deepak Lad, Suranya Subramanian and Dhanashree Prakash Sanap. Ondansetron: A selective 5HT3 receptor antagonist and it advances in drug delivery system. World Journal of Advanced Research and Reviews, 2022, 16(03), 068-077. Article DOI: https://doi.org/10.30574/wjarr.2022.16.3.1275

Copyright © 2022 Author(s) retain the copyright of this article. This article is published under the terms of the Creative Commons Attribution Liscense 4.0

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