Potential of tobacco leaf extract paste (Nicotiana tabacum L.) as a denture cleanser to prevent denture stomatitis

The percentage of use of dentures is relatively high. Dentures with less than optimal cleaning can cause Candida albicans infection, called denture stomatitis. The chemical method of cleaning agents from effervescent tablets of tobacco leaf extract has been studied. However, it is still not optimal, so a combination of mechanical cleaning is needed, namely by making a paste preparation. The aim is to analyze the most effective concentration of tobacco leaf extract in acrylic resin denture cleaning paste in reducing the number of C. Albicans. Type of laboratory experimental research. There were 4 sample groups, namely A: HPAI herbal toothpaste. B: Tobacco leaf extract paste (PEDT) 25%. C: PEDT 50%. D: 75% PEDT. The number of samples for each group was 10. Making Acrylic Resin Plates size 65 mm × 11 mm × 3.5 mm, Making tobacco leaf extract paste 25%, 50%, 75%. Preparation of C. albicans Suspension. Treatment of acrylic plates. Next, calculate the amount of C. Albicans using a spectrophotometer. There was a significant difference (p<0.05) between the control group, the 25% PEDT group, and the 75% PEDT group. A non-significant difference (p>0.05) was found between the control group and the 25% PEDT group and 50 PEDT %, PEDT group 25% to 50% PEDT group, and PEDT group 50% to 75% PEDT group. Effervescent tablets of tobacco leaf extract (Nicotiana tabacum L.) are 75% effective in inhibiting C. Albicans with 30 minutes of soaking time.