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Stability indicating RP-HPLC method development and validation of Terbinafine in pure and pharmaceutical formulation

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  • Stability indicating RP-HPLC method development and validation of Terbinafine in pure and pharmaceutical formulation

M. Lakshmi Surekha *, M. Uma Sampada, T. Yuvasaidurgamouli, Y. SatyaNarayana and T. BharathTeja

Department of Pharmaceutical Analysis, A. M. Reddy Memorial College of Pharmacy, petlurivaripalem, Andhra Pradesh 522601. India.

Research Article
 

World Journal of Advanced Research and Reviews, 2023, 18(03), 264–270
Article DOI: 10.30574/wjarr.2023.18.3.0156
DOI url: https://doi.org/10.30574/wjarr.2023.18.3.0156

Received on 15 December 2022; revised on 30 January 2023; accepted on 02 February 2023

A high performance liquid chromatographic strategy for the assessment of TerbinafineHCl from formulation was created. TerbinafineHCl was chromatographed on a Inertsil ODS-3V (250×4.6, 5µm) and having an inner measurement of 3.9 mm. Mobile phase involving Mobile phase Acetonitrile : 2% IPA (80:20), Mobile phase. The pH of the buffer adjusted to 3.5. The detection was carried out using an ultraviolet detector set at a wavelength of 260 nm. The technique was extended for the stability studies of TerbinafineHCl.

Terbinafine HCl; Stability Studies; RP-HPLC; PDA Detection; Tablet dosage forms; ICH guidelines

https://wjarr.co.in/sites/default/files/fulltext_pdf/WJARR-2023-0156.pdf

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M. Lakshmi Surekha, M. Uma Sampada, T. Yuvasaidurgamouli, Y. SatyaNarayana and T. BharathTeja. Stability indicating RP-HPLC method development and validation of Terbinafine in pure and pharmaceutical formulation. World Journal of Advanced Research and Reviews, 2023, 18(03), 264–270. Article DOI: https://doi.org/10.30574/wjarr.2023.18.3.0156

Copyright © 2023 Author(s) retain the copyright of this article. This article is published under the terms of the Creative Commons Attribution Liscense 4.0

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