Navigating India’s bioeconomy: Analyzing the BioE3 policy, innovation and emerging challenges

India’s bioeconomy is a rapidly growing sector with significant potential for global leadership in biotechnology, biomanufacturing, bio-based solutions, and biopharma. The government’s Bio-E3 (Biotechnology for Economy, Environment and Employment) initiative, a strategic framework aimed at enhancing the bioeconomy, emphasizes the need for stronger research infrastructure, improved regulatory systems, and increased funding for emerging technologies. However, challenges such as regulatory complexities, limited access to finance, and barriers to equitable distribution of bio-based innovations remain. Despite these obstacles, India’s bioeconomy presents opportunities for sustainable economic growth, innovation in healthcare, and addressing global health challenges. This paper explores the current state of India’s bioeconomy, focusing on the Bio-E3 framework, and identifies key challenges hindering its progress. It also proposes actionable strategies, including optimizing regulatory frameworks, expanding public-private partnerships, and fostering research collaborations, to unlock the sector’s full potential.