1 Département of Pedodontia, Faculty of Dentistry, Universitas Kadiri, Kediri, East Java, Indonesia.
2 Département of Prostodontia, Faculty of Dentistry, Universitas Kadiri, Kediri, East Java, Indonesia.
World Journal of Advanced Research and Reviews, 2025, 27(02), 286-291
Article DOI: 10.30574/wjarr.2025.27.2.2867
Received on 27 June 2025; revised on 01 August; accepted on 04 August 2025
Topical fluoride applications are a cornerstone of dental caries prevention, offering proven efficacy through multiple mechanisms. Fluoride enhances remineralization by forming acid-resistant fluorapatite, inhibits demineralization, and disrupts cariogenic bacterial activity. Common formulations include professional treatments like 5% sodium fluoride varnish (reducing caries by 30-45%) and daily-use fluoride toothpaste (1000-5000 ppm), which decrease caries incidence by 24-44%. While concerns about dental fluorosis exist, proper use minimizes risks, making fluoride safe for all ages. Emerging innovations like silver diamine fluoride (SDF) and nanoparticle-enhanced formulations show promise for improved delivery. Topical fluoride remains a cost-effective, versatile solution for caries prevention, supported by extensive evidence and global health guidelines.
Topical fluoride; Caries prevention; Remineralization; Fluoride varnish; Silver diamine fluoride
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Dewi Anggraeni Bibi and Desy Rizkiani Primalia. Topical application fluoride for caries preventive. World Journal of Advanced Research and Reviews, 2025, 27(02), 286-291. Article DOI: https://doi.org/10.30574/wjarr.2025.27.2.2867
Copyright © 2025 Author(s) retain the copyright of this article. This article is published under the terms of the Creative Commons Attribution Liscense 4.0