Reproductive indices and haematological response of male albino rats (Rattus norvegicus) exposed to Carburetor cleaner

Albino rats were exposed to carburetor cleaners with varying routes of exposure using five treatments viz control group1, & groups 2, 3, 4 & 5 representing (inhalatory, feed incorporated, oral and dermal routes) respectively. Haematological parameters as; PCV, HB, RBC, McV, McH, and McHc were evaluated, while the semen analysis such as; Motility quantitative (M1), Debris quantitative (D1), sperm count (C), morphology primordial (Mp), and morphology structure (Ms) were determined. The results revealed the following mean value of PCV for groups 1, 2, 3, 4, and 5 as 47.5, 40.0, 35.0, 20.5, and 23.25 respectively with significant differences (P<0.05) across the group, for HB 15.38, 14.25, 12.10, 8.30 and 8.78 for group 1, 2, 3, 4 and 5 respectively with significant difference (P<0.05) across the group. RBC and McV had a mean value of 5.27 and 9.08, 4.15and 9.59, 3.57 and 10.01, 2.33 and 8.77, 1.85 and 14.66 for groups 1, 2, 3, 4, and 5 respectively with significant differences (P<0.05) across the group. While McH and McHc had a mean value of 2.94 and 0.32, 3.42 and 0.36, 3.45 and 0.35, 3.59 and 0.41, 5.51 and 0.39 for groups 1, 2, 3, 4, and 5 respectively with significant difference (P<0.05) across the group. For semen analysis, M1 was 66.25, 52.5, 43.75, 31.25 and 23.75 for group 1, 2, 3, 4 and 5 respectively, Debris D1 was 6.25, 7.5, 8.75, 28.75 and 7.5 for group 1, 2, 3, 4 and 5 respectively, C and Mp were 53.25 and 6.25, 47.5 and 6.25, 42.0 and 17.75, 36.25 and 27.50, 37.25 and 30.0 for group 1, 2, 3, 4 and 5 respectively also. Finally, Ms was 1.0, 1.0, 1.25, 1.50 and 1.75 for group 1, 2, 3, 4 and 5 respectively. The results generally indicate that carburetor cleaner exerts a negative effect on the body irrespective of the route of exposure and extreme care should be taken when handling and utilization.