Study on association of possible link of ions and insulin resistance in hypertension and diabetes mellitus

To authenticate doubts relating to influence of altered state of some ions in insulin resistance and hypertension we analysed some biomolecules; glucose, insulin, glycated hemoglobin, magnesium, zinc, sodium, potassium and copper from diabetics, non-diabetics and hypertensives. Adopting spectroscopic and immunoassay methods values obtained were statistically evaluated by Anova (Analysis of variance). We observed identical pattern in glucose concentration, glycated hemoglobin and insulin levels among hypertensive and non-hypertensive subjects. However, an aggregated insulin response to glucose was elevated significantly (34.5+3.2 vs 20+2.3 µIU/mL, P<0.05). Zinc and magnesium levels were inversely correlated with HbAIc in insulin dependent diabetics and Non-insulin dependent diabetic (P<0.05). We observed Values increasing in tandem relationship with hypertension. We conclude that while hypertension and insulin resistance may have differential biochemical precursor, a nexus could be established for the place of ionic interferences in these disorders.