Molecular cytogenetic study of Down syndrome and it's health care experience

Down syndrome (DS) is a genetic complex condition which is collection of physical, mental and functional abnormalities that result from trisomy 21, the presence in genome of three rather than the normal two chromosome. Mouse model of DS have shown the involvement of trisomy of all or part of human chromosome 21 or orthologous mouse genomic regions and also provide valuable information into contribution of triplicated gene related to many clinical manifestations in DS. Medical advances, special educational programs, and increasing social acceptance of disabled people in the community have resulted in current trends of normalization and deinstitutionalization of these patients. In this study we performed the detailed literature searches to ameliorate molecular cytogenetic study of Down syndrome and its care.